Mounjaro could assist you to shed some pounds, however it might probably additionally have an effect on your bowel actions. Discover the connection between Mounjaro and constipation.
Mounjaro is likely one of the diabetes drugs that may preserve blood sugar ranges in management and may help folks shed some pounds. These two are essential advantages of this injectable drug, however in addition they have potential unwanted side effects on the physique. Constipation is one such well being downside. Utilizing Mounjaro to handle kind diabetes or drop kilos can have an effect on your bowel actions. You could wrestle in the bathroom as it might probably make your stool tougher. Fortunately there are some things you are able to do to save lots of constipation.
What’s Mounjaro?
Mounjaro is the model title of Tilzepatide and is a medication in a pre-filled pen. It is a blood glucose-lowering drug that’s usually prescribed in sufferers with kind 2 diabetes. “The drug works by activating two receptors known as GLP-1 (glucagon-like peptide-1) and two receptors known as GIP (gastric inhibitory polypeptide). It really works by stimulating the physique’s insulin manufacturing, if obligatory. It additionally limits the quantity of sugar produced by the liver, slows digestion and helps decrease blood sugar ranges.

The US Meals and Drug Administration recommends controlling blood glucose ranges in adults with kind 2 diabetes, quite than kind 2 diabetes or weight reduction. The beginning dose is 2.5 mg and must be subcutaneously injected as soon as every week into the stomach, thighs, or higher arms. After 4 weeks, the dosage might be elevated to five mg. The utmost dosage for this drug is 15 mg.
Mounjaro and constipation: Unwanted side effects of this diabetes medicine
In March 2025, the FDA shared that it obtained adversarial occasion experiences that may very well be associated to folks utilizing tilzepatide at doses larger than these authorized by the company. In keeping with the company, folks skilled signs similar to vomiting, diarrhea, constipation and belly ache. “Constipation is the anticipated unfavorable impact of Munjaro,” says Dr. Kharb.
That is how Mounjaro and constipation are linked:
- Lowered intestinal motion: It will assist you to management your blood sugar and preserve you full for a very long time, however decreased intestinal motion could contribute to constipation.
- I decreased my urge for food: There could also be a hyperlink between munjaro and constipation, as this drug can cut back urge for food. “For those who do not eat or drink an excessive amount of water, you will be much less consumption of fiber and physique fluids,” consultants say. Fiber is a nutrient that helps to let poop undergo collectively. However, correct liquid consumption is essential because it helps to melt the stool.
- Adjustments in fluid absorption: Whereas taking this medicine, stool water could also be absorbed, leading to a stiffer and tougher stool.
Mounjaro and Tuntipation: How you can get aid?
Mounjaro and constipation could also be linked, however don’t fret. You may take easy steps to take easy steps. You must concentrate on easy way of life changes.
1. Keep hydration
Make certain to have sufficient water to appease your stool and assist promote regular bowel actions. I’ve heard of people that emphasize consuming 8-10 glasses of water day by day. Now, this wholesome behavior will assist soften your stool and repeatedly defecate.
2. It is shifting
“Constipation might be prevented and handled by common bodily actions similar to strolling and swimming,” consultants say. Strolling helps digestion, notably after a meal, by stimulating intestinal exercise. This helps stop slowing down intestinal motion.
3. Say sure to textiles
Fiber isn’t just essential for managing your weight. “By looking for a high-fiber weight-reduction plan, you’ll be able to strengthen the majority of your stool and enhance intestine regularity,” says the knowledgeable. Together with greens, they’re wealthy in fiber, in order that they have kidney beans, chia seeds and prunes for constipation administration.
4. medication
There may be stool material softener that may assist save constipation. Some medicine embrace magnesium citrate, sodium docusate, magnesium citrate, and polyethylene glycol. It’s a should to verify along with your physician about these drugs and their simply accessible types.
What are the unwanted side effects of Mounjaro for digestion?
Other than the connection between Mounjaro and constipation, it might probably have an effect on your digestive well being in some ways. Different unwanted side effects of Mounjaro for digestion embrace:
- nausea
- vomiting
- Indigestion
- diarrhea
“These are normally extra intense when you begin the medicine or improve the dosage. Over time, your physique will turn out to be extra adaptable. Subsequently, resistance will develop and result in a lower within the severity of signs,” says Dr. Kharb.

Nonetheless, sure meals and drinks can exacerbate these points. “Oil-based and spicy meals are inclined to stimulate the digestive system, extend discomfort and trigger acid reflux disorder. Additionally, vented drinks contribute to gasoline accumulation and acidity, worsening indigestion,” consultants say.
Mounjaro Lengthy-term unwanted side effects
There’s a hyperlink between Mounjaro and constipation, however taking drugs to handle kind 2 diabetes and shed some pounds could cause unwanted side effects. The checklist consists of nausea and acute pancreatitis. It’s best to seek the advice of your physician in regards to the injection and dosage.
- It may have an effect on not solely muscle mass but additionally fats, which may result in muscle loss.
- Acute pancreatitis is a situation that happens when the pancreas is swollen and infected in a brief time frame, and in line with a research revealed in Cureus, tilzepatide (Mounjaro) unwanted side effects are uncommon, however documented unwanted side effects.
- It might be gallstones.
Associated FAQs
What’s the finest fiber complement for Mounjaro?
Incorporating entire grains, fruits, greens and beans into your weight-reduction plan is one of the best ways to assist digestive well being. These meals assist by growing your fiber consumption and selling common bowel actions. It’s also possible to go to a fiber complement like Metamucil, however seek the advice of your physician first.
Can I take laxatives with Mounjaro?
Laxatives can be utilized to alleviate constipation whereas taking Mounjaro, however ought to solely be taken after consulting your physician. Medical steerage ensures the precise kind and dosage and prevents dependence and undesirable unwanted side effects.