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HealthBixby > Back Pain > Leading Medical Research Demonstrates Benefits of Nerve Stimulation for Lower Back Pain
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Leading Medical Research Demonstrates Benefits of Nerve Stimulation for Lower Back Pain

January 17, 2025 8 Min Read
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Leading Medical Research Demonstrates Benefits of Nerve Stimulation for Lower Back Pain
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Mainstay Medical hopes the information from this research will immediate U.S. payers to increase industrial insurance coverage entry to ReActiv8 remedy. Picture credit score: Prostock-studio (by way of Shutterstock).

A year-long research of Mainstay Medical’s neurostimulation system (CLBP) for the therapy of power low again ache has demonstrated the worth of the system over normal of care (SoC).

The Irish gadget firm’s ReActiv8 Restorative Neurostimulation System is a restorative remedy designed to stimulate the multifidus (MF) nerve, which is answerable for stabilizing a person’s lumbar backbone. The system acquired approval from the U.S. Meals and Drug Administration (FDA) in 2020.

ReActiv8, a surgically implanted gadget, consists of a pulse-generating console and two wires inserted on both facet of the backbone close to the nerves answerable for activating the important thing muscle tissue that stabilize the decrease again, primarily the MF. has been.

Mainstay’s research, whose outcomes had been printed within the journal Ache and Remedy, randomly assigned 203 sufferers to therapy or management teams.

The research met its major endpoint of change in imply enchancment in Oswestry Incapacity Index (ODI) scores between therapy and management teams at 1-year follow-up, with an ODI of -19.7 ± 1.4 within the ReActiv8 group versus – A statistical significance of two.9 was achieved. ±1.4 in management arm.

Secondary endpoints achieved within the management group of this research included imply enchancment in low again ache, measured utilizing the 11-point Numerical Score Scale (NRS), and the EQ-5D-5L score. Imply enhancements in well being care-related high quality of life had been included.

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The research steering committee mentioned the outcomes demonstrated that ReActiv8 Restorative Neurostimulation supplies superior enhancements in sufferers’ lives past SoC measures similar to bodily remedy and ache medicines.

Mainstay Medical CEO Jason Hannon commented: “These high-quality information demonstrating the therapeutic efficacy of ReActiv8 in comparison with present normal of care meaningfully add to the rising scientific proof on ReActiv8 and spotlight the vital function of this remedy in refractory mechanical remedy. It has been firmly established that “again ache sufferers”.

“We’re leveraging these information and the compelling outcomes from the ReActiv8-B scientific trial and quite a few different research to additional have interaction U.S. payers and enhance industrial assist for this transformative remedy. We sit up for increasing insurance coverage entry and considerably lowering general well being care prices.”

ReActiv8 is commercially out there in Europe, Australia, and the UK, and is presently the one remedy permitted in the USA for the therapy of CLBP brought on by MF dysfunction.

MF failure is regarded as a significant explanation for low again ache (LBP) and may result in CLBP over time. In keeping with the World Well being Group (WHO), 619 million individuals worldwide are affected by LBP. The report predicts that LBP will enhance to 843 million instances worldwide by 2050, on account of elements similar to inhabitants development and ageing, bodily inactivity, weight problems, and muscle weak spot which may be inherited.

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