Trulicity and Ozempic are each weekly GLP-1 agonist injections used to decrease blood sugar ranges in sufferers with sort 2 diabetes.
On this article, we’ll evaluate the principle similarities and variations that can assist you determine which drug is best for you.
What are Trulicity and Ozempic?
Trulicity and Ozempic are identify model injectable medicine categorized as GLP-1 agonists. Each are permitted by the U.S. Meals and Drug Administration (FDA) to handle blood sugar ranges in sufferers with sort 2 diabetes.
Trulicity is permitted for youngsters 10 years and older and adults, whereas Ozempic is barely permitted for adults.
Each medicine may also help with weight reduction and may assist stop strokes, coronary heart assaults, and untimely loss of life in folks with sort 2 diabetes and pre-existing coronary heart illness.
See beneath for extra info. Every part you want to find out about Trulicity and Every part you want to find out about Ozempic.
Why select Trulicity or Ozempic?
When you’ve got sort 2 diabetes, your physician might prescribe one in every of these medicine, particularly when you’ve got insulin resistance, persistently excessive blood sugar ranges (particularly after meals), or problem sustaining a wholesome weight.
Research have proven that GLP-1 agonists corresponding to Ozempic and Trulicity might promote weight reduction, however neither is FDA permitted for this goal.
When prescribed off-label (in a fashion not formally permitted by the FDA), these medicine could also be used to enhance insulin sensitivity and assist weight reduction even in folks with out sort 2 diabetes. Make sure to take it beneath the steering of your physician.
For extra info, see: Every part you want to find out about Trulicity and Every part you want to find out about Ozempic.
How are Trulicity and Ozempic comparable?
Trulicity and Ozempic have some similarities.
Not a substitute for insulin
These medicine don’t exchange insulin, however they will complement insulin in managing blood sugar ranges over the long run.
It helps decrease blood sugar step by step with out inflicting acute hypoglycemia (hypoglycemia).
When insulin resistance decreases, much less insulin could also be wanted to handle blood sugar ranges.
It’s an injection that’s taken as soon as per week.
Each are solely accessible as weekly subcutaneous (beneath the pores and skin) injections.
It is very important preserve consistency by having your remedy completed on the identical day and on the similar time every week.
have comparable unwanted side effects
Trulicity and Ozempic share many unwanted side effects, together with:
- nausea
- vomiting
- diarrhea
- belly ache
- urge for food suppression
- weight reduction
- constipation
- fatigue
- Hypoglycemia (if used with insulin)
Though uncommon, each medicine can enhance the danger of growing medullary thyroid most cancers (MTC). When you’ve got a private or household historical past of MTC, it is best to keep away from utilizing these medicine.
Moreover, the FDA issued black field warnings for each medicine relating to their affiliation with elevated danger of thyroid most cancers.
See beneath for extra info. Trulicity unwanted side effects: what you want to know and Ozempic unwanted side effects: what you want to know.
They trigger weight reduction and decrease blood sugar ranges
Each Trulicity and Ozempic successfully decrease blood sugar ranges and promote weight reduction.
Though not particularly permitted by the FDA for weight reduction, many individuals expertise a lack of 5% or extra of their physique weight whereas taking these medicine.
It isn’t permitted for weight reduction, so there is no such thing as a dosage advisable particularly for that goal.
In case you are contemplating weight administration choices, Trulicity or Ozempic could also be good choices to debate together with your healthcare supplier.
See beneath for extra info. Trulicity and Weight Loss: Can Trulicity Assist You Lose Weight? and Does Ozempic assist with weight reduction?
Will be taken with or with out meals
In contrast to insulin, which might quickly decrease blood sugar ranges, this medicine may be taken with or with out meals.
The perfect time to take it’s the time you are most probably to recollect it every week.
For extra info, see: Trulicity Dosage: How A lot Ought to I Take? and Ozempic Dosage Information: How A lot Ought to I Take?
Though not required, consuming a lightweight meal earlier than and after the injection might cut back nausea.
Select bland meals like bananas, rice, toast, applesauce, and soup. Weight-reduction plan performs an vital position when adapting to new medicines, so watch out concerning the meals you select.
For extra info, see: Meals to keep away from when taking Trulicity and Meals to keep away from whereas taking Ozempic.
What’s the distinction between Trulicity and Ozempic?
Though these medicine are comparable, there are vital variations.
Completely different lively components
Trulicity and Ozempic are each GLP-1 agonists, however have totally different lively components. Trulicity accommodates dulaglutide, whereas Ozempic accommodates semaglutide.
In case you are allergic to any of those components, seek the advice of your physician earlier than beginning remedy as critical unwanted side effects might happen.
Ozempic could also be more practical.
An vital examine evaluating semaglutide (Ozempic) and dulaglutide (Trulicity) in sufferers with sort 2 diabetes discovered that semaglutide, at each excessive and low doses, was more practical at enhancing glycemic management and weight reduction, and comparable It was discovered to have a security profile of
When you’ve got extreme insulin resistance and have problem sustaining a wholesome weight, ask your physician if Ozempic is best for you.
FAQ
Can I change between the 2?
Sure, it’s doable to modify between Trulicity and Ozempic.
Nonetheless, to attenuate the danger of significant unwanted side effects, your well being care supplier might suggest ready one week after you final took one dose earlier than beginning the opposite. There’s a gender.
In case you are allergic to any of the lively components in Ozempic’s semaglutide or Trulicity’s dulaglutide, you shouldn’t change them.
In case you are experiencing critical unwanted side effects from one drug, your physique might tolerate them otherwise, so attempting the opposite could also be a greater possibility.
Can I take each on the similar time?
No, Trulicity and Ozempic can’t be taken collectively, regardless that their lively components are totally different.
Two doses of GLP-1 agonists could cause critical unwanted side effects, together with harmful hypoglycemia, which may be life-threatening if untreated.
Should you by accident take each medicines on the similar time or inside 2 days of one another, contact your physician or search emergency remedy straight away.
Which medication is true for me?
The choice between Trulicity and Ozempic needs to be made collectively by you and your healthcare supplier primarily based in your well being historical past, objectives, way of life, and preferences.
At all times take into account lively components and doable allergic reactions. Moreover, test your medical health insurance protection to see which medicines are in your most popular drug checklist so you possibly can select an inexpensive, long-term possibility.
There aren’t any generic variations of Trulicity or Ozempic, however your physician might counsel extra inexpensive alternate options.
For extra info, Every part you want to find out about Trulicity and Every part you want to find out about Ozempic. Was this text useful? Tell us by clicking Sure or No beneath.
